The CD-47 targeting therapeutics market is projected to grow at a CAGR of 42.9%, claims Roots Analysis
Upon realizing the potential of this novel
target, industry stakeholders have initiated several R&D efforts focused on
exploiting the use of CD47 as an effective biomarker for the diagnosis and
treatment purposes.
Roots
Analysis has announced the
addition of “CD-47 Targeting Therapeutics
Market, 2021-2035” report
to its list of offerings.
In recent years, the focus of the research
community has shifted towards the development of novel treatment modalities,
such as T- cell immunotherapies, that exhibit high efficacy. CD-47, owing to its increased expression on the surface of cancer cells, has
emerged as a cancer immune checkpoint biomarker.
To order this 190+ page report, which
features 142+ figures, please visit https://www.rootsanalysis.com/reports/cd-47-targeting-therapeutics-market.html
Key Market Insights
Over 75 CD-47 drug candidates are under
various phases of development
52% of the pipeline candidates are currently
in preclinical and discovery stages, while more than 48% therapies are being
evaluated in clinical stages with most candidates being in early clinical
stages (41.6%); 3.9% and 2.6% of clinical candidates being evaluated in phase
II and phase III respectively.
~50 companies claim to be engaged in the
development of CD-47 therapeutics, globally
Since 2015, 13 companies have been
established in this domain. Further, around 44% of the industry stakeholders
are small companies. In addition, majority (47%) of the CD-47 therapeutics
developers are based in North America, primarily in the US.
Several clinical trials evaluating CD-47 targeting
therapeutics have been registered worldwide
Clinical research activity, in terms of
number of trials registered, is reported to have increased at a CAGR of 34.1%,
during the period 2015-2020. Of the total, close to 13% of the studies have
already been completed, followed by active trials that are actively recruiting
patients (46.7%).
Partnership activity within this domain has
increased at a CAGR of 25.7%, between 2016 and 2020
Clinical trial agreements emerged as the most
popular type of partnership model adopted by industry stakeholders, followed by
product development and commercialization agreements (25%), licensing
agreements (25%), and services agreements (7.1%).
USD 3.3+ billion has been invested by both
private and public investors
It is important to mention that, between 2016
and 2021, majority of the funding amount was raised through secondary offerings
(46.5%), venture capital rounds (45%), IPO (15.6%) and debt financing (7.4%).
North America is anticipated to capture over
85% of the market share, by 2035
The market will be primarily driven by sales
of CD-47 based therapeutics designed as biologics (over 60%), followed by those
developed as small molecules (over 39%). Further, CD-47 based therapies
targeting non-small cell lung cancer will capture the dominant share (23%) of
the market (in terms of sales-based revenues); this trend is unlikely to change
in the foreseen future.
To request a sample copy / brochure of this
report, please visit
https://www.rootsanalysis.com/reports/cd-47-targeting-therapeutics-market.html
Key Questions Answered
§ Who are the leading players engaged in the
development of CD47 targeting therapeutics?
§ Which are the key drugs being developed
across early and late stages of development?
§ Which companies are actively involved in
conducting clinical trials for their therapeutics?
§ What is the evolving trend related to the
focus of publications related to CD47 targeting therapeutics?
§ What kind of partnership models are commonly
adopted by industry stakeholders?
§ Who are the key investors in this domain?
§ Who are the key opinion leaders / experts in
this field?
§ What are the evolving social media trends
related to CD47 targeting therapeutics?
§ What are the different initiatives undertaken
by big pharma players for the development of CD47 therapeutics in the recent past?
§ How is the current and future opportunity
likely to be distributed across key market segments?
The financial opportunity within the CD-47
targeting therapeutics market has been analyzed across the following segments:
§ Type
of Molecule
- Biologics
- Small
molecules
§ Target
Indications
- Acute Myeloid Leukemia
- Colorectal Neoplasms
- Diffuse-Large Cell Lymphoma
- Myelodysplastic Syndromes
- Non-Hodgkin Lymphoma
- Non-Small Cell Lung Cancer
- Oral Muscositis
- Ovarian Epithelial Cancer
- Small Cell Lung Cancer
§ Key
Players
§ Key
Geographical Regions
- US
- France
- Germany
- Italy
- Spain
- UK
- Australia
- China
- India
- Israel
The research includes detailed profiles of 10+
developers by (listed below); the profiles also feature an overview of the
developer, its financial information (if available), recent developments and an
informed future outlook.
|
§ Abpro |
|
§ ALX Oncology |
|
§ Apmonia Therapeutics |
|
§ Arch Oncology |
|
§ Aurigene |
|
§ Bristol Myers Squibb |
|
§ EpicentRx |
|
§ Forty Seven |
|
§ ImmuneOncia Therapeutics |
|
§ ImmuneOnco Biopharmaceuticals |
|
§ Innovent Biologics |
|
§ KAHR Medical |
|
§ Light Chain Bioscience |
|
§ Morphiex |
|
§ Trillium Therapeutics |
For additional details, please visit
https://www.rootsanalysis.com/reports/cd-47-targeting-therapeutics-market.html or email sales@rootsanalysis.com
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Contact:
Ben Johnson
+1 (415) 800 3415
+44 (122) 391 1091
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